Peroxisome proliferator‐activated receptor gamma (PPARγ) regulates lactase expression and activity in the gut

Peroxisome proliferator‐activated receptor gamma (PPARγ) regulates lactase expression and activity in the gut

Abstract Lactase (LCT) deficiency affects approximately 75% of the world's adult population and may lead to lactose malabsorption and intolerance. Currently, the regulation of LCT gene expression remains poorly known. Peroxisome proliferator activator receptorγ (PPARγ) is a key player in carboh...

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Main Authors: Mathurin Fumery, Silvia Speca, Audrey Langlois, Anne‐Marie Davila, Caroline Dubuquoy, Marta Grauso, Anthony Martin Mena, Martin Figeac, Daniel Metzger, Christel Rousseaux, Jean‐Frederic Colombel, Laurent Dubuquoy, Pierre Desreumaux, Benjamin Bertin
Format: Article
Language:English
Published: Springer Nature 2017-09-01
Series:EMBO Molecular Medicine
Subjects:
hypolactasia
intestinal epithelial cells
lactase
lactose intolerance
PPARgamma
Online Access:https://doi.org/10.15252/emmm.201707795
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https://doi.org/10.15252/emmm.201707795

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