The molecular clock drives motivated locomotion and time-of-day-dependent firing patterns in mouse dopaminergic neurons

The molecular clock drives motivated locomotion and time-of-day-dependent firing patterns in mouse dopaminergic neurons

Abstract Though circadian locomotor rhythms are primarily driven by the suprachiasmatic nucleus, voluntary motor behavior also requires dopaminergic neuron (DAN) activity. However, it is unknown whether DAN molecular and electrophysiological properties and rhythmic motor behaviors are dependent on a...

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Main Authors: Ananya Swaroop, Jodi R. Paul, Laura J. McMeekin, Ashley M. Barnett, Alana M. Colafrancesco, Drèson L. Russell, Camille M. Smith, Micah S. Simmons, Laura A. Volpicelli-Daley, Rita M. Cowell, Karen L. Gamble
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:npj Biological Timing and Sleep
Online Access:https://doi.org/10.1038/s44323-025-00044-2
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https://doi.org/10.1038/s44323-025-00044-2

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