Computational design and molecular insights into acetylcholinesterase inhibitors from Aristolochia indica for Alzheimer’s disease therapy

Abstract Alzheimer’s disease (AD) remains a major neurodegenerative disorder with limited effective treatments, necessitating the search for novel acetylcholinesterase (AChE) inhibitors to mitigate cognitive decline. While synthetic inhibitors pose concerns regarding toxicity and bioavailability, na...

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Bibliographic Details
Main Authors: Srinivasarao Mande, Lalitha Repudi, Sanchari Goswami, Nadia Psalms Gangavarapu, Hamid Ghaffoori Hasan, Kumaraswamy Gandla
Format: Article
Language:English
Published: Springer 2025-05-01
Series:Discover Chemistry
Subjects:
Online Access:https://doi.org/10.1007/s44371-025-00197-w
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