Restrictions on the use of valproate in female patients of reproductive age: the updated recommendations based on recent clinical data

Restrictions on the use of valproate in female patients of reproductive age: the updated recommendations based on recent clinical data

For more than half a century, valproic acid (VA) has been a first-line drug to control seizures in various forms of epilepsy and status epilepticus; VA is also used in bipolar disorders. However, the accumulated clinical evidence indicates negative outcomes of pregnancies in women receiving valproat...

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Main Authors: G. N. Avakyan, D. V. Blinov, G. G. Avakyan, E. S. Akarachkova, S. G. Burd, P. N. Vlasov, K. V. Voronkova, V. I. Guzeva, I. A. Zhidkova, E. A. Katunina, D. I. Korabelnikov, A. V. Lebedeva, L. V. Lipatova, E. A. Morozova, O. M. Oleinikova, I. G. Rudakova
Format: Article
Language:Russian
Published: IRBIS LLC 2019-07-01
Series:Эпилепсия и пароксизмальные состояния
Subjects:
epilepsy
pregnancy
teratogenicity
serious congenital malformations
attention deficit hyperactivity disorder
adhd
autism
autism spectrum disorders
asd
valproic acid
valproate
anti-epileptic drugs
aep
pregnancy prevention program
Online Access:https://www.epilepsia.su/jour/article/view/472
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