Newly-diagnosed rheumatoid arthritis patients have elevated levels of plasma extracellular vesicles with protein cargo altered towards inflammatory processes

Newly-diagnosed rheumatoid arthritis patients have elevated levels of plasma extracellular vesicles with protein cargo altered towards inflammatory processes

Abstract Extracellular vesicles (EVs) are implicated in rheumatoid arthritis (RA) but have mainly been assessed in RA patients taking disease modifying anti-rheumatic drugs. EVs are nanoparticles important in cell-cell communication and their molecular cargo are biomarker candidates. We characterize...

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Main Authors: Anne Rydland, Fatima Heinicke, Tuula A. Nyman, Anne-Marie Siebke Trøseid, Siri T. Flåm, Maria Stensland, Johanna Gehin, Joakim Eikeland, Reidun Øvstebø, Maria Dahl Mjaavatten, Benedicte A. Lie
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Extracellular vesicles
Rheumatoid arthritis
DMARD Naïve
Inflammatory markers
Online Access:https://doi.org/10.1038/s41598-025-96325-8
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https://doi.org/10.1038/s41598-025-96325-8

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