SIV proviruses seeded later in infection are harbored in short-lived CD4+ T cells

SIV proviruses seeded later in infection are harbored in short-lived CD4+ T cells

Summary: The human immunodeficiency virus (HIV) can persist in a latent form as integrated DNA (provirus) in resting CD4+ T cells unaffected by antiretroviral therapy. Despite being a major obstacle for eradication efforts, it remains unclear which infected cells survive, persist, and ultimately ent...

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Bibliographic Details
Main Authors: Narmada Sambaturu, Emily J. Fray, Vivek Hariharan, Fengting Wu, Carolin Zitzmann, Francesco R. Simonetti, Dan H. Barouch, Janet D. Siliciano, Robert F. Siliciano, Ruy M. Ribeiro, Alan S. Perelson, Carmen Molina-París, Thomas Leitner
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Cell Reports
Subjects:
CP: Microbiology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124725004346
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http://www.sciencedirect.com/science/article/pii/S2211124725004346

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