The effect of non-local coupling of fibroblasts on pacing dynamics in a 2D tissue: a simulation study

Abstract Although myocytes in healthy hearts are usually coupled to nearest neighbours via gap junctions, under conditions such as fibrosis, in scar tissue, or across ablation lines, myocytes can uncouple from their neighbours. However it has been experimentally observed that electrical conduction c...

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Bibliographic Details
Main Authors: S. Sridhar, Richard H. Clayton
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-99674-6
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