Apolipoprotein E imbalance in the cerebrospinal fluid of Alzheimer’s disease patients

Apolipoprotein E imbalance in the cerebrospinal fluid of Alzheimer’s disease patients

Abstract Objective The purpose of this study was to examine the levels of cerebrospinal fluid (CSF) apolipoprotein E (apoE) species in Alzheimer’s disease (AD) patients. Methods We analyzed two CSF cohorts of AD and control individuals expressing different APOE genotypes. Moreover, CSF samples from...

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Main Authors: Matthew Paul Lennol, Irene Sánchez-Domínguez, Inmaculada Cuchillo-Ibañez, Elena Camporesi, Gunnar Brinkmalm, Daniel Alcolea, Juan Fortea, Alberto Lleó, Guadalupe Soria, Fernando Aguado, Henrik Zetterberg, Kaj Blennow, Javier Sáez-Valero
Format: Article
Language:English
Published: BMC 2022-11-01
Series:Alzheimer’s Research & Therapy
Subjects:
Alzheimer’s disease
apoE
Biomarker
Aberrant complexes
Cerebrospinal fluid
Glycoform imbalance
Online Access:https://doi.org/10.1186/s13195-022-01108-2
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https://doi.org/10.1186/s13195-022-01108-2

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