Timosaponin B-II suppresses gastric cancer cell proliferation and induces apoptosis via the Nrf2/miR-455-3p/KLF6 pathway

Timosaponin B-II suppresses gastric cancer cell proliferation and induces apoptosis via the Nrf2/miR-455-3p/KLF6 pathway

Abstract Background Gastric cancer (GC), known for its aggressive growth and metastasis, remains a leading cause of cancer-related mortality. Although Timosaponin B-II (TB-II) from Anemarrhena asphodeloides has shown anticancer potential, its underlying mechanisms in GC are not yet fully understood....

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Bibliographic Details
Main Authors: Qiaoyan Cui, Ruijie Zhang, Shiqiao Zhao, Jian Wang, Yafen Dong, Xuesong Bai, Ye Chen, Yan Qiu
Format: Article
Language:English
Published: Springer 2025-05-01
Series:Discover Oncology
Subjects:
Timosaponin B-II
Gastric cancer(GC)
Nrf2
miR-455-3p
KLF6
Online Access:https://doi.org/10.1007/s12672-025-02650-9
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https://doi.org/10.1007/s12672-025-02650-9

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