Microglia mediated by LAG3 regulate astrocyte morphogenesis in the brain white matter

Summary: Microglia display dynamic morphological and functional heterogeneity during brain development, yet the molecular mechanisms governing their regional specialization remain unclear. We report that lymphocyte-activation gene 3 (Lag3) is highly expressed in white matter amoeboid microglia at po...

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Bibliographic Details
Main Authors: Sihan Li, Mengtian Zhang, Jie Qin, Yanyan Wang, Runhua Yang, Fen Ji, Jianwei Jiao
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Cell Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2211124725008836
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