Differential influence of 1,8-Cineol on distinct hypoxia-related immune alterations in human monocytes

Differential influence of 1,8-Cineol on distinct hypoxia-related immune alterations in human monocytes

Abstract 1,8-Cineol is a natural plant-based therapeutic agent and is commonly used to treat a broad range of acute and chronic airway inflammatory diseases. 1,8-Cineol has recently been shown to attenuate the checkpoint molecule PDL-1 in circulating monocytes in patients with chronic Otitis media (...

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Bibliographic Details
Main Authors: Nele Jagodzinski, Anke Leichtle, Reinhard Depping, Kirstin Plötze-Martin, Samer G. Hakim, Karl-Ludwig Bruchhage, Ralph Pries
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Hypoxia
1,8-Cineol
Monocytes
Cytokines
Adhesion molecules
FGF-7
Online Access:https://doi.org/10.1038/s41598-025-97314-7
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https://doi.org/10.1038/s41598-025-97314-7

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