The interplay of ferroptosis and oxidative stress in the pathogenesis of aortic dissection

The interplay of ferroptosis and oxidative stress in the pathogenesis of aortic dissection

Aortic dissection (AD) is a life-threatening vascular condition marked by the separation or tearing of the aortic media. Ferroptosis, a form of iron-dependent programmed cell death, occurs alongside lipid peroxidation and the accumulation of reactive oxygen species (ROS). The relationship between fe...

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Bibliographic Details
Main Authors: Zhaoshan Zhang, Haichao Wang, Xi Kan, Xiaozhao Zhang, Senping Xu, Jie Cai, Jiawei Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Pharmacology
Subjects:
aortic dissection
ferroptosis
vascular smooth muscle cells
oxidative stress
ROS
endothelial cells
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1519273/full
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