Conserved GTPase OLA1 promotes efficient translation on D/E-rich mRNA

Abstract The TRAFAC (translation factors) GTPase OLA1 plays a critical role in various stress responses and is implicated in the regulation of tumor progression. It is conserved from bacteria to eukaryotes and regulates the translation through binding to the ribosome. Here, we report the cryo-electr...

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Bibliographic Details
Main Authors: Ting Yu, Xin Li, Wanlin Dong, Qixin Zhou, Qingrong Li, Zisuo Du, Fuxing Zeng
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-56797-8
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