CAR-macrophages targets CD26 to eliminate chronic myeloid leukemia stem cells

Abstract Background Chronic myeloid leukemia stem cells (CML-LSCs), which exhibit resistance to tyrosine kinase inhibitors (TKIs), are the leading cause of treatment failure and recurrence in chronic myeloid leukemia (CML). This highlights the urgent need for novel therapies aimed at eliminating the...

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Bibliographic Details
Main Authors: Jiang Guoyun, Qin Yuefeng, Huang Zhenglan, Yuan Zuowei, Zhou Hongyan, Yuan Ying, Feng Wenli
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Experimental Hematology & Oncology
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Online Access:https://doi.org/10.1186/s40164-025-00608-9
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