Flavivirus NS4B proteins do not form homodimers: discrepancies with an AlphaFold-based oligomeric model
In flaviviruses such as Dengue, Zika or West Nile virus (DENV, ZIKV or WNV), non-structural protein 4B (NS4B) participates in membrane remodeling during infection and is critical for virulence and host immunity. Despite the important roles and confirmed drug target status for NS4B, no detailed struc...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-01-01
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| Series: | Computational and Structural Biotechnology Journal |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2001037025001497 |
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