Immunomodulatory Effects of Halichondrin Isolated from Marine Sponges and Its Synthetic Analogs in Oncological Applications

Immunomodulatory Effects of Halichondrin Isolated from Marine Sponges and Its Synthetic Analogs in Oncological Applications

Marine natural products comprise unique chemical structures and vast varieties of biological activities. This review aims to summarize halichondrin, a marine natural product, and its synthetic analogs along with its therapeutic properties and mechanisms. Halichondrin and its analogs, derived from ma...

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Bibliographic Details
Main Authors: Dinusha Shiromala Dissanayake, Dineth Pramuditha Nagahawatta, Jung-Suck Lee, You-Jin Jeon
Format: Article
Language:English
Published: MDPI AG 2024-09-01
Series:Marine Drugs
Subjects:
halichondrin
eribulin
cancer therapeutics
E7389
microtubule disruption
Online Access:https://www.mdpi.com/1660-3397/22/9/426
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