Green synthesis of novel hexahydroquinolines and 6-amino-2-oxopyridine-3,5-dicarbonitriles incorporating sulfaguanidine via [3 + 3] atom combination

Green synthesis of novel hexahydroquinolines and 6-amino-2-oxopyridine-3,5-dicarbonitriles incorporating sulfaguanidine via [3 + 3] atom combination

The synthesis of sulfa drugs has received extensive interest from researchers for their broad spectrum of biological activities. In this context, N-Carbamimidoyl-4-((5,5-dimethyl-3-oxocyclohex-1-en-1-yl)amino)benzenesulfonamide 3 was readily prepared and its Michael addition reactions towards activa...

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Bibliographic Details
Main Authors: Amr M. Abdelmoniem, Mostafa E. Salem, Mahmoud Hassan Mohamed Allam, Mortaga M. Abou-Krisha, Ibrahim O. Althobaiti, Said A.S. Ghozlan, Khaled E. Azmy, Ismail A. Abdelhamid
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Results in Chemistry
Subjects:
Sulfaguanidine,
Cyclic enaminones,
2-Cyanoacetamide,
Tetrahydroquinolines,
Michael addition,
[3 + 3] Atom combination,
Online Access:http://www.sciencedirect.com/science/article/pii/S2211715625000487
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