Characterization and propagation of tumor initiating cells derived from colorectal liver metastases: trials, tribulations and a cautionary note.

Characterization and propagation of tumor initiating cells derived from colorectal liver metastases: trials, tribulations and a cautionary note.

Tumor initiating cells (TIC) are increasingly being put forward as a potential target for intervention within colorectal cancer. Whilst characterisation and outgrowth of these cells has been extensively undertaken in primary colorectal cancers, few data are available describing characteristics withi...

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Main Authors: Mark I James, Lynne M Howells, Ankur Karmokar, Jennifer A Higgins, Peter Greaves, Hong Cai, Ashley Dennison, Matthew Metcalfe, Giuseppe Garcea, David M Lloyd, David P Berry, William P Steward, Karen Brown
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0117776
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https://doi.org/10.1371/journal.pone.0117776

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