PARP enzymes and mono-ADP-ribosylation: advancing the connection from interferon-signalling to cancer biology

ADP-ribosyltransferases of the PARP family encompass a group of enzymes with variegated regulatory functions in cells, ranging from DNA damage repair to the control of cell-cycle progression and immune response. Over the years, this knowledge has led to the use of PARP1/2 inhibitors as mainstay phar...

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Bibliographic Details
Main Authors: Barbara Morone, Giovanna Grimaldi
Format: Article
Language:English
Published: Cambridge University Press 2024-01-01
Series:Expert Reviews in Molecular Medicine
Subjects:
Online Access:https://www.cambridge.org/core/product/identifier/S1462399424000139/type/journal_article
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