Transfer RNA-derived fragment tRF-36 modulates varicose vein progression via human vascular smooth muscle cell Notch signaling

Transfer RNA-derived fragment tRF-36 modulates varicose vein progression via human vascular smooth muscle cell Notch signaling

Varicose veins are a prevalent vascular disorder affecting millions of individuals worldwide, and we previously reported transfer RNA-derived fragment (tRF) involvement in varicose veins. This study investigated the role of tRF-36 in varicose vein pathogenesis. Varicose veins and adjacent normal vas...

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Bibliographic Details
Main Authors: Chen Guojun, Yu Chong, Shi Yu, Cai Danna, Zhou Bin
Format: Article
Language:English
Published: De Gruyter 2025-04-01
Series:Open Life Sciences
Subjects:
varicose veins
trf-36
human vascular smooth muscle cells
notch pathway
phenotypic switching
Online Access:https://doi.org/10.1515/biol-2025-1075
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https://doi.org/10.1515/biol-2025-1075

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