Suspensions of antibiotics in self-emulsifying oils as a novel approach to formulate eye drops with substances which undergo hydrolysis in aqueous environment

The aim of this study was to develop eye-drops with cefuroxime (CEF) sodium or vancomycin (VAN) hydrochloride, antibiotics that are instable in water. Anhydrous self-emulsifying oils (SEO) are proposed as a carrier and antibiotics are suspended. In the contact with tear fluid, the formulation should...

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Bibliographic Details
Main Authors: Katarzyna Krzeminska, Malgorzata Sznitowska, Magdalena Wroblewska, Eliza Wolska, Katarzyna Winnicka
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Drug Delivery
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Online Access:https://www.tandfonline.com/doi/10.1080/10717544.2024.2372279
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