Single cell atlas of canine natural killer cells identifies distinct circulating and tissue resident gene profiles

Single cell atlas of canine natural killer cells identifies distinct circulating and tissue resident gene profiles

IntroductionNatural killer (NK) cells in mice and humans are key effectors of the innate immune system with complex immunoregulatory functions, and diverse subsets have been identified with distinct characteristics and roles. Companion dogs with spontaneous cancer have been validated as models of hu...

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Main Authors: Aryana M. Razmara, Marshall Lammers, Sean J. Judge, William J. Murphy, Cameron E. Gaskill, William T.N. Culp, Alicia A. Gingrich, Zachary S. Morris, Robert B. Rebhun, C. Titus Brown, David M. Vail, Michael S. Kent, Robert J. Canter
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Immunology
Subjects:
canine (dog)
comparative
NK cell
single cell RNA sequencing (scRNAseq)
transcriptomics
tissue resident
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1571085/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1571085/full

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