The effects of SGLT2i on cardiac metabolism in patients with HFpEF: Fact or fiction?

The effects of SGLT2i on cardiac metabolism in patients with HFpEF: Fact or fiction?

Abstract The rising prevalence of Type 2 diabetes (T2D) has been closely associated with an increased incidence of cardiovascular diseases, particularly heart failure with preserved ejection fraction (HFpEF). Cardiometabolic disturbances in T2D, such as insulin resistance, hyperglycemia, and dyslipi...

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Main Authors: Francesca Cinti, Renzo Laborante, Luigi Cappannoli, Cassandra Morciano, Shawn Gugliandolo, Alfredo Pontecorvi, Francesco Burzotta, Maria Donniacuo, Donato Cappetta, Giuseppe Patti, Andrea Giaccari, Domenico D’Amario
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Cardiovascular Diabetology
Subjects:
Diabetes
Heart failure
Metabolism
SGLT2i
Precision medicine
Microvascular dysfunction
Online Access:https://doi.org/10.1186/s12933-025-02767-9
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https://doi.org/10.1186/s12933-025-02767-9

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