Anchorage accurately assembles anchor-flanked synthetic long reads

Abstract Modern sequencing technologies allow for the addition of short-sequence tags, known as anchors, to both ends of a captured molecule. Anchors are useful in assembling the full-length sequence of a captured molecule as they can be used to accurately determine the endpoints. One representative...

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Bibliographic Details
Main Authors: Xiaofei Carl Zang, Xiang Li, Kyle Metcalfe, Tuval Ben-Yehezkel, Ryan Kelley, Mingfu Shao
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Algorithms for Molecular Biology
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Online Access:https://doi.org/10.1186/s13015-025-00288-4
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