Calcium-sensor proteins but not bicarbonate ion activate retinal photoreceptor membrane guanylyl cyclase in photoreceptors

Retinal membrane guanylyl cyclase (RetGC), regulated by guanylyl cyclase activating proteins (GCAPs) via negative calcium-feedback, is one of the most critically important enzymes in vertebrate rod and cone physiology, enabling their sensitivity to light. It was also reported that, similarly to olfa...

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Bibliographic Details
Main Authors: Igor V. Peshenko, Elena V. Olshevskaya, Alexander M. Dizhoor
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Molecular Neuroscience
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Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2024.1509366/full
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