Role of TGFβ-activated cancer-associated fibroblasts in the resistance to checkpoint blockade immunotherapy
Immune checkpoint blockers (ICBs) have revolutionized cancer treatment by enabling durable responses. However, most patients showed resistance and limited efficacy. Elucidating mechanisms of resistance is imperative to extend the clinical utility of ICBs. Emerging evidence highlights cancer-associat...
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| Main Author: | |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-05-01
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| Series: | Frontiers in Oncology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2025.1602452/full |
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