JUMLAH LEUKOSIT DAN DERAJAT KLINIS PENDERITA INFEKSI DENGUE DI RSUD DR. H. ABDUL MOELOEK LAMPUNG

Dengue hemorrhagic fever (DHF) is an infectious disease caused by the dengue virus transmitted by mosquitoes. Hematological abnormalities in the form of a decrease in the number of leukocytes which are influenced by the clinical degree due to stress on the bone marrow can occur in cases of DHF. The...

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Main Authors: Hidayat, Hetti Rusmini, Toni Prasetia, Henri Setiawan
Format: Article
Language:English
Published: Poltekkes Kemenkes Tanjungpinang 2021-07-01
Series:Jurnal Ilmu dan Teknologi Kesehatan Terpadu
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Online Access:https://ejurnal.poltekkes-tanjungpinang.ac.id/index.php/jkstl/article/view/10
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author Hidayat
Hetti Rusmini
Toni Prasetia
Henri Setiawan
author_facet Hidayat
Hetti Rusmini
Toni Prasetia
Henri Setiawan
author_sort Hidayat
collection DOAJ
description Dengue hemorrhagic fever (DHF) is an infectious disease caused by the dengue virus transmitted by mosquitoes. Hematological abnormalities in the form of a decrease in the number of leukocytes which are influenced by the clinical degree due to stress on the bone marrow can occur in cases of DHF. The decrease or increase in the number of leukocytes was thought to be related to the clinical degree of DHF in previous studies. This study aimed to determine the relationship between the number of leukocytes and the clinical degree in patients with dengue infection. This study used an observational analytic method with a cross-sectional approach. The population consisted of 39 patients with dengue infection. The data on the results of the examination of the number of leukocytes and the clinical degree were obtained from medical record documents. Data analysis was performed using the Spearman correlation test. 39 study subjects suffering from dengue infection consisting of clinical degrees I (30.8%), II (61.5%), and III (7.7%). The leukocyte count was between 4,000-10,000/µL (59%) and the leukocyte count <4,000/µL (41%). The mean number of leukocytes at clinical grade I was 4.183/µL, at clinical grade II was 4.754/µL and clinical-grade III was 6.100/µL. The results of statistical tests with the Spearman correlation test obtained the value of r = -0.121 and the value of p = 0.462 (p> 0.05). There was no significant relationship between the leukocyte count and the clinical degree of dengue infection. Future researchers are expected to increase the number of research samples so that they can get all clinical degrees of DHF.
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spelling doaj-art-4019d77806f74763a03a17878c0a24772025-01-08T05:33:09ZengPoltekkes Kemenkes TanjungpinangJurnal Ilmu dan Teknologi Kesehatan Terpadu2797-03292021-07-0111455210.53579/jitkt.v1i1.1023JUMLAH LEUKOSIT DAN DERAJAT KLINIS PENDERITA INFEKSI DENGUE DI RSUD DR. H. ABDUL MOELOEK LAMPUNGHidayat0Hetti Rusmini1Toni Prasetia2Henri Setiawan3Kepala Instalasi Laboratorium Patologi Klinik RSUD Dr. H. Abdul Moeloek Provinsi LampungDepartemen Farmakologi Fakultas Kedokteran Universitas MalahayatiDepartemen Ilmu Penyakit Dalam Fakultas Kedokteran Universitas MalahayatiProgram Studi Kedokteran Fakultas Kedokteran Universitas MalahayatiDengue hemorrhagic fever (DHF) is an infectious disease caused by the dengue virus transmitted by mosquitoes. Hematological abnormalities in the form of a decrease in the number of leukocytes which are influenced by the clinical degree due to stress on the bone marrow can occur in cases of DHF. The decrease or increase in the number of leukocytes was thought to be related to the clinical degree of DHF in previous studies. This study aimed to determine the relationship between the number of leukocytes and the clinical degree in patients with dengue infection. This study used an observational analytic method with a cross-sectional approach. The population consisted of 39 patients with dengue infection. The data on the results of the examination of the number of leukocytes and the clinical degree were obtained from medical record documents. Data analysis was performed using the Spearman correlation test. 39 study subjects suffering from dengue infection consisting of clinical degrees I (30.8%), II (61.5%), and III (7.7%). The leukocyte count was between 4,000-10,000/µL (59%) and the leukocyte count <4,000/µL (41%). The mean number of leukocytes at clinical grade I was 4.183/µL, at clinical grade II was 4.754/µL and clinical-grade III was 6.100/µL. The results of statistical tests with the Spearman correlation test obtained the value of r = -0.121 and the value of p = 0.462 (p> 0.05). There was no significant relationship between the leukocyte count and the clinical degree of dengue infection. Future researchers are expected to increase the number of research samples so that they can get all clinical degrees of DHF.https://ejurnal.poltekkes-tanjungpinang.ac.id/index.php/jkstl/article/view/10clinical degreesecondary dengue infectionleukocytes
spellingShingle Hidayat
Hetti Rusmini
Toni Prasetia
Henri Setiawan
JUMLAH LEUKOSIT DAN DERAJAT KLINIS PENDERITA INFEKSI DENGUE DI RSUD DR. H. ABDUL MOELOEK LAMPUNG
Jurnal Ilmu dan Teknologi Kesehatan Terpadu
clinical degree
secondary dengue infection
leukocytes
title JUMLAH LEUKOSIT DAN DERAJAT KLINIS PENDERITA INFEKSI DENGUE DI RSUD DR. H. ABDUL MOELOEK LAMPUNG
title_full JUMLAH LEUKOSIT DAN DERAJAT KLINIS PENDERITA INFEKSI DENGUE DI RSUD DR. H. ABDUL MOELOEK LAMPUNG
title_fullStr JUMLAH LEUKOSIT DAN DERAJAT KLINIS PENDERITA INFEKSI DENGUE DI RSUD DR. H. ABDUL MOELOEK LAMPUNG
title_full_unstemmed JUMLAH LEUKOSIT DAN DERAJAT KLINIS PENDERITA INFEKSI DENGUE DI RSUD DR. H. ABDUL MOELOEK LAMPUNG
title_short JUMLAH LEUKOSIT DAN DERAJAT KLINIS PENDERITA INFEKSI DENGUE DI RSUD DR. H. ABDUL MOELOEK LAMPUNG
title_sort jumlah leukosit dan derajat klinis penderita infeksi dengue di rsud dr h abdul moeloek lampung
topic clinical degree
secondary dengue infection
leukocytes
url https://ejurnal.poltekkes-tanjungpinang.ac.id/index.php/jkstl/article/view/10
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