STUDY OF THE STABILITY OF THE SUBSTANCE 3-[2-(4-PHENYL-1-PIPERAZINO)-2-OXOETHYL]QUINAZOLINE-4(3Н)-ONE UNDER STRESSFUL CONDITIONS

STUDY OF THE STABILITY OF THE SUBSTANCE 3-[2-(4-PHENYL-1-PIPERAZINO)-2-OXOETHYL]QUINAZOLINE-4(3Н)-ONE UNDER STRESSFUL CONDITIONS

The aim of the research was to study the stability of a new pharmaceutical substance 3-[2-(4-phenyl-1-piperazino)-2-oxoethyl]quinazoline-4(3Н)-one under stress conditions.Materials and methods. The study was conducted in accordance with the recommendations of the ICH guidelines. The object of the st...

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Bibliographic Details
Main Authors: T. A. Gendugov, A. A. Glushko, A. A. Ozerov, L. I. Shcherbakova
Format: Article
Language:Russian
Published: Volgograd State Medical University, Pyatigorsk Medical and Pharmaceutical Institute 2021-01-01
Series:Фармация и фармакология (Пятигорск)
Subjects:
quinazoline-4(3h)-one derivative
pharmaceutical substance
stress testing
stress test modeling
thermolysis
photolysis
hydrolysis
high-performance liquid chromatography
photostability
thermalstability
gromacs
orca
Online Access:https://www.pharmpharm.ru/jour/article/view/729
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