Origin of bistability underlying mammalian cell cycle entry
Abstract Precise control of cell proliferation is fundamental to tissue homeostasis and differentiation. Mammalian cells commit to proliferation at the restriction point (R‐point). It has long been recognized that the R‐point is tightly regulated by the Rb–E2F signaling pathway. Our recent work has...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2011-04-01
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| Series: | Molecular Systems Biology |
| Online Access: | https://doi.org/10.1038/msb.2011.19 |
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