TPM4 overexpression drives colon epithelial cell tumorigenesis by suppressing differentiation and promoting proliferation

Objective: The high morbidity and mortality associated with colorectal cancer (CRC) and the recent increases in early-onset CRC obviate the need for novel methods to detect and treat this disease, particularly at early stages. We hypothesize that aberrant expression of genes involved in the crypt-lu...

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Bibliographic Details
Main Authors: Rajsumeet S. Macwan, Giulio Ferrero, Barbara Pardini, Alessio Naccarati, Piotr B. Kozlowski, Michael J. Papetti
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Neoplasia: An International Journal for Oncology Research
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Online Access:http://www.sciencedirect.com/science/article/pii/S1476558624001349
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