Sensitivity evaluation of methods for screening JAK2 exon 12 mutations based on heteroduplex and HRM analysis

Background. According to WHO guidelines, one of the criteria for diagnosis of polycythemia vera is the presence of somatic mutations in exon 12 of the JAK2 gene, but to date there is no universally accepted simple method to analyze these mutations. We have previously proposed two methods for screeni...

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Bibliographic Details
Main Authors: T. N. Subbotina, A. A. Shalyova, A. I. Shevchenko, E. A. Pozdysheva, Ya. A. Voytsekhovskaya, K. O. Mironov
Format: Article
Language:Russian
Published: ABV-press 2024-01-01
Series:Онкогематология
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Online Access:https://oncohematology.abvpress.ru/ongm/article/view/901
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