Kv11.1-dependent senescence activates a lethal immune response via tumor necrosis factor alpha

Understanding the complex relationship between cancer and immune surveillance is essential for leveraging the immune system to control tumor growth. In our study, we discovered that activating the Kv11.1 potassium channel in ER+ breast cancer cells induces a senescent phenotype, which in turn trigge...

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Bibliographic Details
Main Authors: Maedeh Vakili Saatloo, Davide Delisi, Najmeh Eskandari, Carsten Krieg, Saverio Gentile
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Neoplasia: An International Journal for Oncology Research
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Online Access:http://www.sciencedirect.com/science/article/pii/S1476558625000272
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