Cyclosporin A Decreases Human Macrophage Interleukin-6 Synthesis at Post-Transcriptional Level

Cyclosporin A Decreases Human Macrophage Interleukin-6 Synthesis at Post-Transcriptional Level

In addition to its well-established effect on T cells, cyclosporin A (CsA) also inhibits inflammatory cytokine production by macrophages. However, little is known about the mechanism of action of CsA on macrophage cytokine production. We measured the effect of CsA on basal and phorbol-myristate-acet...

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Main Authors: Juan E. Losa García, Ana M. Rodríguez López, María Rosa Martín De Cabo, Fernando Mateos Rodríguez, Jesús Pérez Losada, Rogelio González Sarmiento, Antonio Jiménez López, José Luis Pérez Arellano
Format: Article
Language:English
Published: Wiley 1999-01-01
Series:Mediators of Inflammation
Subjects:
Cyclosporin A
Interleukin-6
Macrophage
U937.
Online Access:http://dx.doi.org/10.1080/09629359990423
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http://dx.doi.org/10.1080/09629359990423

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