Association between mutations in a thyX-hsdS.1 region and para-aminosalicylic acid resistance in Mycobacterium tuberculosis clinical isolates

Association between mutations in a thyX-hsdS.1 region and para-aminosalicylic acid resistance in Mycobacterium tuberculosis clinical isolates

Although para-aminosalicylic acid (PAS) has been used to treat tuberculosis agent for decades, its mechanisms of resistance are still not thoroughly understood. Previously, sporadic studies showed that certain mutations in the thyX-hsdS.1 region caused PAS resistance in M. tuberculosis, but a compre...

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Bibliographic Details
Main Authors: Rong Zeng, Lina He, Baoyue Zhang, Yangbo Hu, Jifang Yu, Shanshan Yang, Jing Gu, Zhilong Wu, Jiaoyu Deng
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Emerging Microbes and Infections
Subjects:
Mycobacterium tuberculosis
PAS
resistance
thyX-hsdS.1
mutations
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2023.2276339
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https://www.tandfonline.com/doi/10.1080/22221751.2023.2276339

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