Characterization of lactylation-based phenotypes and molecular biomarkers in sepsis-associated acute respiratory distress syndrome

Characterization of lactylation-based phenotypes and molecular biomarkers in sepsis-associated acute respiratory distress syndrome

Abstract Sepsis-associated acute respiratory distress syndrome (ARDS) is a heterogeneous disease with high morbidity and mortality. Lactylation plays a crucial role in sepsis and sepsis-induced lung injury. This study aimed to identify distinct lactylation-based phenotypes in patients with sepsis-as...

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Bibliographic Details
Main Authors: Yiheng Wang, An Wei, Zixuan Su, Yunyi Shi, Xinqiu Li, Lixian He
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Lactylation
Sepsis-associated acute respiratory distress syndrome
Heterogeneity
Phenotype
Molecular biomarkers
Circulating immune cells
Online Access:https://doi.org/10.1038/s41598-025-96969-6
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https://doi.org/10.1038/s41598-025-96969-6

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