Multicentric Reticulohistiocytosis Presenting with Papulonodular Skin Lesions and Arthritis Mutilans
Multicentric reticulohistiocytosis is a rare multisystem disorder of unknown etiology that is characterized by erosive polyarthritis and papulonodular lesions on the skin, mucous membranes, and internal organs. We report the case of a 54-year-old female who was misdiagnosed as having rheumatoid arth...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Case Reports in Rheumatology |
| Online Access: | http://dx.doi.org/10.1155/2013/201563 |
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| author | Raya Saba Shawn G. Kwatra Bishwas Upadhyay Aibek E. Mirrakhimov Farah N. Khan |
| author_facet | Raya Saba Shawn G. Kwatra Bishwas Upadhyay Aibek E. Mirrakhimov Farah N. Khan |
| author_sort | Raya Saba |
| collection | DOAJ |
| description | Multicentric reticulohistiocytosis is a rare multisystem disorder of unknown etiology that is characterized by erosive polyarthritis and papulonodular lesions on the skin, mucous membranes, and internal organs. We report the case of a 54-year-old female who was misdiagnosed as having rheumatoid arthritis and underwent numerous joint replacement surgeries for progressively destructive arthritis in her hands, shoulders, hips, and knees. The patient finally received a diagnosis of multicentric reticulohistiocytosis after histopathological examination of the patient’s left knee arthroplasty which revealed a diffuse histiocytic infiltrate, multinucleated giant cells, and finely granulated eosinophilic cytoplasm with a ground-glass appearance. |
| format | Article |
| id | doaj-art-3f794ef09f8b46279f3ba176c969c23a |
| institution | Kabale University |
| issn | 2090-6889 2090-6897 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Rheumatology |
| spelling | doaj-art-3f794ef09f8b46279f3ba176c969c23a2025-02-03T01:26:44ZengWileyCase Reports in Rheumatology2090-68892090-68972013-01-01201310.1155/2013/201563201563Multicentric Reticulohistiocytosis Presenting with Papulonodular Skin Lesions and Arthritis MutilansRaya Saba0Shawn G. Kwatra1Bishwas Upadhyay2Aibek E. Mirrakhimov3Farah N. Khan4Department of Internal Medicine, Saint Joseph Hospital, 2900 N. Lake Shore, Chicago, IL 60657, USADepartment of Internal Medicine, Saint Joseph Hospital, 2900 N. Lake Shore, Chicago, IL 60657, USADepartment of Internal Medicine, Saint Joseph Hospital, 2900 N. Lake Shore, Chicago, IL 60657, USADepartment of Internal Medicine, Saint Joseph Hospital, 2900 N. Lake Shore, Chicago, IL 60657, USADepartment of Internal Medicine, Saint Joseph Hospital, 2900 N. Lake Shore, Chicago, IL 60657, USAMulticentric reticulohistiocytosis is a rare multisystem disorder of unknown etiology that is characterized by erosive polyarthritis and papulonodular lesions on the skin, mucous membranes, and internal organs. We report the case of a 54-year-old female who was misdiagnosed as having rheumatoid arthritis and underwent numerous joint replacement surgeries for progressively destructive arthritis in her hands, shoulders, hips, and knees. The patient finally received a diagnosis of multicentric reticulohistiocytosis after histopathological examination of the patient’s left knee arthroplasty which revealed a diffuse histiocytic infiltrate, multinucleated giant cells, and finely granulated eosinophilic cytoplasm with a ground-glass appearance.http://dx.doi.org/10.1155/2013/201563 |
| spellingShingle | Raya Saba Shawn G. Kwatra Bishwas Upadhyay Aibek E. Mirrakhimov Farah N. Khan Multicentric Reticulohistiocytosis Presenting with Papulonodular Skin Lesions and Arthritis Mutilans Case Reports in Rheumatology |
| title | Multicentric Reticulohistiocytosis Presenting with Papulonodular Skin Lesions and Arthritis Mutilans |
| title_full | Multicentric Reticulohistiocytosis Presenting with Papulonodular Skin Lesions and Arthritis Mutilans |
| title_fullStr | Multicentric Reticulohistiocytosis Presenting with Papulonodular Skin Lesions and Arthritis Mutilans |
| title_full_unstemmed | Multicentric Reticulohistiocytosis Presenting with Papulonodular Skin Lesions and Arthritis Mutilans |
| title_short | Multicentric Reticulohistiocytosis Presenting with Papulonodular Skin Lesions and Arthritis Mutilans |
| title_sort | multicentric reticulohistiocytosis presenting with papulonodular skin lesions and arthritis mutilans |
| url | http://dx.doi.org/10.1155/2013/201563 |
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