Low-dose adrenaline, promethazine, and hydrocortisone in the prevention of acute adverse reactions to antivenom following snakebite: a randomised, double-blind, placebo-controlled trial.

Low-dose adrenaline, promethazine, and hydrocortisone in the prevention of acute adverse reactions to antivenom following snakebite: a randomised, double-blind, placebo-controlled trial.

<h4>Background</h4>Envenoming from snakebites is most effectively treated by antivenom. However, the antivenom available in South Asian countries commonly causes acute allergic reactions, anaphylactic reactions being particularly serious. We investigated whether adrenaline, promethazine,...

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Main Authors: H Asita de Silva, Arunasalam Pathmeswaran, Channa D Ranasinha, Shaluka Jayamanne, Senarath B Samarakoon, Ariyasena Hittharage, Ranjith Kalupahana, G Asoka Ratnatilaka, Wimalasiri Uluwatthage, Jeffrey K Aronson, Jane M Armitage, David G Lalloo, H Janaka de Silva
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-05-01
Series:PLoS Medicine
Online Access:https://journals.plos.org/plosmedicine/article/file?id=10.1371/journal.pmed.1000435&type=printable
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https://journals.plos.org/plosmedicine/article/file?id=10.1371/journal.pmed.1000435&type=printable

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