Role of Lysosomes in Silica-Induced Inflammasome Activation and Inflammation in Absence of MARCO
MARCO is the predominant scavenger receptor for recognition and binding of silica particles by alveolar macrophages (AM). Previously, it was shown that mice null for MARCO have a greater inflammatory response to silica, but the mechanism was not described. The aim of this study was to determine the...
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Main Authors: | Rupa Biswas, Raymond F. Hamilton, Andrij Holian |
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Format: | Article |
Language: | English |
Published: |
Wiley
2014-01-01
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Series: | Journal of Immunology Research |
Online Access: | http://dx.doi.org/10.1155/2014/304180 |
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