Extracellular Vesicles Present in Bone Marrow Mesenchymal Stromal/Stem Cell Conditioned Media Restore Spermatogenesis in Azoospermic Mice

Extracellular Vesicles Present in Bone Marrow Mesenchymal Stromal/Stem Cell Conditioned Media Restore Spermatogenesis in Azoospermic Mice

Background: We aimed to examine the therapeutic efficacy of exosome-enriched conditioned media (CM), known for its high concentration of extracellular vesicles (EVs), in comparision with mesenchymal stromal/stem cells (MSCs) in treating non-obstructive azoospermia.Materials and Methods: In this expe...

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Main Authors: Rano Zhankina, Afshin Zare, Alireza Afshar, Arezoo Khoradmehr, Mohammad Reza Dorvash, Farhad Rahmanifar, Nader Tanideh, Omid Koohi Hosseinabadi, Ali Arabi Monfared, Shahrokh Zare, Nadiar Mussin, Asset Askerovich Kaliyev, Ulanbek Zhanbyrbekuly, Amin Tamadon
Format: Article
Language:English
Published: Royan Institute (ACECR), Tehran 2025-07-01
Series:International Journal of Fertility and Sterility
Subjects:
azoospermia
mesenchymal stromal/stem cell
extracellular vesicles
Online Access:https://www.ijfs.ir/article_718640_661f36cea6a83bbfb14c9cfd44eab25f.pdf
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https://www.ijfs.ir/article_718640_661f36cea6a83bbfb14c9cfd44eab25f.pdf

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