Impact of myelodysplasia‐related and additional gene mutations in intensively treated patients with NPM1‐mutated AML

Impact of myelodysplasia‐related and additional gene mutations in intensively treated patients with NPM1‐mutated AML

ABSTRACT This study aimed to evaluate the impact of the myelodysplasia‐related gene (MRG) as well as additional gene mutations on outcomes in intensively treated patients with NPM1‐mutated (NPM1mut) AML. Targeted DNA sequencing of 263 genes was performed in 568 NPM1mut AML patients (median age: 59 y...

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Main Authors: Sibylle Cocciardi, Maral Saadati, Nina Weiß, Daniela Späth, Silke Kapp‐Schwoerer, Isabelle Schneider, Annika Meid, Verena I. Gaidzik, Sabrina Skambraks, Walter Fiedler, Michael W. M. Kühn, Ulrich Germing, Karin T. Mayer, Michael Lübbert, Elli Papaemmanuil, Felicitas Thol, Michael Heuser, Arnold Ganser, Lars Bullinger, Axel Benner, Hartmut Döhner, Konstanze Döhner
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:HemaSphere
Online Access:https://doi.org/10.1002/hem3.70060
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https://doi.org/10.1002/hem3.70060

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