Perivascular Arrest of CD8+ T Cells Is a Signature of Experimental Cerebral Malaria.

Perivascular Arrest of CD8+ T Cells Is a Signature of Experimental Cerebral Malaria.

There is significant evidence that brain-infiltrating CD8+ T cells play a central role in the development of experimental cerebral malaria (ECM) during Plasmodium berghei ANKA infection of C57BL/6 mice. However, the mechanisms through which they mediate their pathogenic activity during malaria infec...

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Main Authors: Tovah N Shaw, Phillip J Stewart-Hutchinson, Patrick Strangward, Durga B Dandamudi, Jonathan A Coles, Ana Villegas-Mendez, Julio Gallego-Delgado, Nico van Rooijen, Egor Zindy, Ana Rodriguez, James M Brewer, Kevin N Couper, Michael L Dustin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1005210&type=printable
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https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1005210&type=printable

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