Integrative analysis of H&E and IHC identifies prognostic immune subtypes in HPV related oropharyngeal cancer

Abstract Background Deep learning techniques excel at identifying tumor-infiltrating lymphocytes (TILs) and immune phenotypes in hematoxylin and eosin (H&E)-stained slides. However, their ability to elucidate detailed functional characteristics of diverse cellular phenotypes within tumor immune...

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Main Authors: Sumanth Reddy Nakkireddy, Inyeop Jang, Minji Kim, Linda X. Yin, Michael Rivera, Joaquin J. Garcia, Kathleen R. Bartemes, David M. Routman, Eric. J. Moore, Chadi N. Abdel-Halim, Daniel J. Ma, Kathryn M. Van Abel, Tae Hyun Hwang
Format: Article
Language:English
Published: Nature Portfolio 2024-10-01
Series:Communications Medicine
Online Access:https://doi.org/10.1038/s43856-024-00604-w
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