The RNA-methyltransferase Misu (NSun2) poises epidermal stem cells to differentiate.
Homeostasis of most adult tissues is maintained by balancing stem cell self-renewal and differentiation, but whether post-transcriptional mechanisms can regulate this process is unknown. Here, we identify that an RNA methyltransferase (Misu/Nsun2) is required to balance stem cell self-renewal and di...
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| Main Authors: | Sandra Blanco, Agata Kurowski, Jennifer Nichols, Fiona M Watt, Salvador Aznar Benitah, Michaela Frye |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2011-12-01
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| Series: | PLoS Genetics |
| Online Access: | https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1002403&type=printable |
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