Interaction of cardiac leiomodin with the native cardiac thin filament.

Every heartbeat depends on cyclical contraction-relaxation produced by the interactions between myosin-containing thick and actin-based thin filaments (TFs) arranged into a crystalline-like lattice in the cardiac sarcomere. Therefore, the maintenance of thin filament length is crucial for myocardium...

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Bibliographic Details
Main Authors: Madison Little, Cristina M Risi, Tania M Larrinaga, Mason D Summers, Tyler Nguyen, Garry E Smith, Jennifer Atherton, Carol C Gregorio, Alla S Kostyukova, Vitold E Galkin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3003027
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