Hypoxia Induced Downregulation of Na+/H+ Exchanger-1 Activity Decreases Tumor Cell Proliferation
Objectives: Hypoxia and acidosis are the hallmarks of proliferative tumor microenvironment which can modulate the expression and function of Na+/H+ exchanger-1 (NHE1) via hypoxia inducible factor 1 (Hif). Here, we investigate the severity and time dependent effects of chronic hypoxia on NHE1 activit...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Galenos Publishing House
2025-03-01
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| Series: | Ankara Üniversitesi Tıp Fakültesi Mecmuas |
| Subjects: | |
| Online Access: | https://www.ankaratipfakultesimecmuasi.net/articles/hypoxia-induced-downregulation-of-nalesssupgreaterlesssupgreaterhlesssupgreaterlesssupgreater-exchanger-1-activity-decreases-tumor-cell-proliferation/doi/atfm.galenos.2025.98624 |
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