Incidence of Metastasis in the Central Nervous System in Advanced Breast Cancer Treated With CDK 4/6 Inhibitors: A Multicenter, Retrospective Study

Incidence of Metastasis in the Central Nervous System in Advanced Breast Cancer Treated With CDK 4/6 Inhibitors: A Multicenter, Retrospective Study

Abstract Central nervous system (CNS) metastasis remains a major cause of mortality in advanced breast cancer (ABC). While cyclin‐dependent kinase 4/6 inhibitors (CDKIs) combined with endocrine therapy (ET) delay resistance in hormone receptor (HR)‐positive and human epidermal growth factor receptor...

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Bibliographic Details
Main Authors: Yan‐Ling Wen, Xi‐Wen Bi, Xue‐Wen Zhang, Si‐Fen Wang, Chang Jiang, Li Wang, Yong‐Yi Zhong, Yuan‐Yuan Huang, Jian‐Li Zhao, Qian‐Jun Chen, Cong Xue, Zhong‐Yu Yuan
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:MedComm
Subjects:
advanced breast cancer
CDK 4/6 inhibitor
CNS metastasis
endocrine therapy
Online Access:https://doi.org/10.1002/mco2.70221
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