Fatal poisoning case involving drug interaction due to the inhibition of cytochrome P450

Fatal poisoning case involving drug interaction due to the inhibition of cytochrome P450

Introduction. Cytochrome P450 (CYP) enzymes are responsible for the metabolism of various drugs and chemicals. The forensic pathologist should consider not only pharmacodynamic interactions by multiple drugs but also the pharmacokinetic drug interactions of each drug in the case of multiple drug ing...

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Bibliographic Details
Main Authors: Kinoshita Hiroshi, Tanaka Naoko, Kumihashi Mitsuru, Jamal Mostofa, Ito Asuka, Yamashita Tadayoshi, Ameno Kiyoshi
Format: Article
Language:English
Published: Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade 2021-01-01
Series:Vojnosanitetski Pregled
Subjects:
autopsy
cytochrome p-450 enzyme system
drug interactions
ethanol
forensic pathology
phenothiazines
poisoning
psychotropic drugs
Online Access:http://www.doiserbia.nb.rs/img/doi/0042-8450/2021/0042-84501900090K.pdf
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http://www.doiserbia.nb.rs/img/doi/0042-8450/2021/0042-84501900090K.pdf

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