Melanoma Development and Progression Are Associated with Rad6 Upregulation and β-Catenin Relocation to the Cell Membrane

We have previously demonstrated that Rad6 and β-catenin enhance each other's expression through a positive feedback loop to promote breast cancer development/progression. While β-catenin has been implicated in melanoma pathogenesis, Rad6 function has not been investigated. Here, we examined the...

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Bibliographic Details
Main Authors: Karli Rosner, Darius R. Mehregan, Evangelia Kirou, Judith Abrams, Seongho Kim, Michelle Campbell, Jillian Frieder, Kelsey Lawrence, Brittany Haynes, Malathy P. V. Shekhar
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Journal of Skin Cancer
Online Access:http://dx.doi.org/10.1155/2014/439205
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