Differential HIV-1 Proviral Defects in Children vs. Adults on Antiretroviral Therapy

Differential HIV-1 Proviral Defects in Children vs. Adults on Antiretroviral Therapy

HIV-1 proviral landscapes were investigated using near-full-length HIV single-genome sequencing on blood samples from five children with vertically acquired infection and on ART for ~7–9 years. Proviral structures were compared to published datasets in children prior to ART, children on short-term A...

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Bibliographic Details
Main Authors: Jenna M. Hasson, Mary Grace Katusiime, Adam A. Capoferri, Michael J. Bale, Brian T. Luke, Wei Shao, Mark F. Cotton, Gert van Zyl, Sean C. Patro, Mary F. Kearney
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Viruses
Subjects:
HIV in children
HIV reservoir
HIV persistence
HIV proviruses
HIV latency
intact provirus
Online Access:https://www.mdpi.com/1999-4915/17/7/961
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