Influenza A virus N-linked glycosylation sites with very low glycan occupancy: identification, evolutionary dynamics, and impact on virus biology

Influenza A virus N-linked glycosylation sites with very low glycan occupancy: identification, evolutionary dynamics, and impact on virus biology

Introduction: Influenza A virus (IAV) is a common pathogen of the human respiratory tract that causes both seasonal endemics and intermittent pandemics. The IAV major surface protein and antigen, hemagglutinin (HA), is extensively glycosylated, with 12 N-linked glycosylation sites in A(H3N2)2013 IAV...

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Main Authors: Dr Irina Alymova, Dr Wen-Pin Tzeng, Dr Alexander Jureka, Dr John Barr, Dr Dongxia Wang, Dr Betlehem Mekonnen, Mr Shane Gansebom, Dr Ian York
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:International Journal of Infectious Diseases
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971224007112
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